Chloro-1,4-dimethyl-9H-carbazole Derivatives Displaying Anti-HIV Activity.

Carmela SaturninoFedora GrandeStefano AquaroAnna CarusoDomenico IacopettaMaria Grazia BonomoPasquale LongoDominique Schols Maria Stefania Sinicropi

Published in: Molecules (Basel, Switzerland) (2018)

a preliminary biological investigation on the synthesized small series of chloro-1,4-dimethyl-9H-carbazoles has been carried out. Among all tested compounds, a nitro-derivative (3b) showed the most interesting profile representing a suitable lead for the development of novel anti-HIV drugs.

Keyphrases

antiretroviral therapy
hiv positive
hiv infected
hiv testing
human immunodeficiency virus
hepatitis c virus
hiv aids
men who have sex with men
water soluble
drug induced
structure activity relationship