Acute onset paraplegia in a case of granulomatosis with polyangitis (GPA) - an unusual complication.
Debashis MaikapPrasanta PadhanPublished in: Modern rheumatology case reports (2020)
Granulomatosis with polyangiitis (GPA) is a rare multisystem autoimmune disease of unknown aetiology with only a few reported cases about spinal cord involvement in the literature. We report on the case of an established GPA presented with acute onset bilateral lower limb weakness, urinary retention and faecal incontinence consistent with transverse myelitis. Contrast-enhanced MRI scanning revealed T2 hyperintensity extending from the T1 to conus medularis, without any gadolinium enhancement features suggestive of long segment myelitis. He was successfully treated with I.V IG followed by Rituximab.
Keyphrases
- contrast enhanced
- lower limb
- magnetic resonance imaging
- diffusion weighted
- liver failure
- magnetic resonance
- spinal cord
- computed tomography
- drug induced
- diffusion weighted imaging
- respiratory failure
- aortic dissection
- systematic review
- diffuse large b cell lymphoma
- neuropathic pain
- single cell
- intensive care unit
- myasthenia gravis