Histology, fusion status, and outcome in metastatic rhabdomyosarcoma: A report from the Children's Oncology Group.
Erin R RudzinskiJames R AndersonYueh-Yun ChiJulie M Gastier-FosterCaroline AstburyFrederic G BarrStephen X SkapekDouglas S HawkinsBrenda J WeigelAlberto PappoWilliam H MeyerMichael A ArnoldLisa A TeotDavid M ParhamPublished in: Pediatric blood & cancer (2017)
In contrast to low- or intermediate-risk RMS, in metastatic RMS, clinical risk factors have the most impact on patient outcome. PAX-FOXO1 fusion is more common in patients with a high Oberlin score, but fusion status is not an independent biomarker of prognosis.