Kinetics of peripheral blood neutrophils in severe coronavirus disease 2019.
Mieke MetzemaekersSeppe CambierMarfa BlanterJennifer VandoorenAna Carolina de CarvalhoBert Malengier-DevliesLore VanderbekeCato JacobsSofie CoenenErik MartensNoëmie PörtnerLotte VanbrabantPierre Van MolYannick Van HerckNathalie Van AerdeGreet HermansJan GunstAlexandre BorinBruna Toledo N PereiraArilson Bernardo Dos Sp GomesStéfanie Primon MuraroGabriela Fabiano de SouzaAlessandro S FariasJosé Luiz Proenca-ModenaMarco Aurélio R Vinolonull nullPedro Elias MarquesCarine WoutersEls WautersSofie StruyfPatrick MatthysGhislain OpdenakkerRafael Elias MarquesJoost WautersMieke GouwyMieke GouwyPublished in: Clinical & translational immunology (2021)
Our study provides detailed insights into the kinetics of neutrophil phenotype and function in severe COVID-19 patients, and supports the concept of an increased neutrophil activation state in the circulation.