Secukinumab in United States Biologic-Naïve Patients With Psoriatic Arthritis: Results From the Randomized, Placebo-Controlled CHOICE Study.
Tien NguyenMelvin ChurchillRobert LevinGuillermo ValenzuelaJoseph Frank MerolaPhilip S HelliwellAna Maria OrbaiJose U ScherArthur KavanaughFarid KianifardChauncy RollinsRenato CalheirosOlivier ChambenoitPublished in: The Journal of rheumatology (2022)
SEC 300 mg led to rapid and significant improvements over placebo in symptoms of PsA in this heavier population of US-only, biologic-naïve patients. Findings were consistent with previous studies and suggest that SEC 300 mg is a safe and efficacious first-line biologic treatment for patients with PsA. [ClinicalTrials.gov: NCT02798211].
Keyphrases
- placebo controlled
- double blind
- rheumatoid arthritis
- prostate cancer
- phase iii
- end stage renal disease
- ejection fraction
- newly diagnosed
- phase ii
- clinical trial
- chronic kidney disease
- open label
- radical prostatectomy
- prognostic factors
- peritoneal dialysis
- ankylosing spondylitis
- squamous cell carcinoma
- systemic lupus erythematosus
- depressive symptoms
- radiation therapy
- case control