von Willebrand Factor and Factor VIII Clearance in Perioperative Hemophilia A Patients.
Iris van MoortLaura H BukkemsJessica M HeijdraRoger E G SchutgensBritta A P Laros-van GorkomLaurens NieuwenhuizenFelix J M van der MeerKarin FijnvandraatPaula YpmaMoniek P M de MaatFrank W G LeebeekKarina MeijerJeroen EikenboomRon A A MathôtMarjon H Cnossennull nullPublished in: Thrombosis and haemostasis (2020)
VWF:Ag and VWF:GPIbM levels increase postoperatively, most significantly in patients with blood type non-O or medium risk surgery. Lower VWF antigen levels did not lead to clinically relevant higher FVIII clearance. VWF:Ag or VWF:GPIbM levels were not associated with perioperative hemorrhage.