Contrasting effects of phosphatidylinositol 4,5-bisphosphate on cloned TMEM16A and TMEM16B channels.

Chau M TaKathryn E AchesonNils J G RorsmanRemco C JongkindPaolo Tammaro

Published in: British journal of pharmacology (2017)

PIP2 acts as a modifier of TMEM16A and TMEM16B channel gating. Drugs interacting with PIP2 signalling may affect TMEM16A and TMEM16B channel gating and have potential uses in basic science and implications for therapy.

Keyphrases

public health
stem cells
risk assessment
climate change