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Elevated Serum Vinculin in Patients with HBV/HCV-Associated Liver Cirrhosis and Hepatocellular Carcinoma: A Pilot Study.

Abdallah EssaEnas Said EssaSara Mahmoud El-DeebHossam Eldin Mostafa SeleemMuthana Al SahlawiOmar Ahmed Al-OmairSomaia Shehab-Eldeen
Published in: Biologics : targets & therapy (2023)
Patients with HBVor HCV-induced liver cirrhosis and HCC have significantly higher serum levels of vinculin than do controls. This might point to a potential role for vinculin in the development of HCC. More research into how this protein affects the development of HCC at the molecular level could lead to better clinical treatments and the development of new molecular therapies.
Keyphrases
  • hepatitis c virus
  • human immunodeficiency virus
  • oxidative stress
  • single molecule
  • binding protein
  • small molecule