Percutaneous lumbar annular puncture: A rat model to study intervertebral disc degeneration and pain-related behavior.

Richard A WawroseBrandon K CouchMalcom DombrowskiStephen R Chen Anthony A OyekanQing DongDong WangChaoming ZhouJoseph ChenKarthik ModaliMarit JohnsonZachary Sedor-SchiffhauerT Kevin HitchensTao JinKevin M BellJoon Y LeeGwendolyn A SowaNam V Vo

Published in: JOR spine (2022)

This is the first reported study of the successful establishment of a reproducible rodent model of a percutaneous lumbar annular puncture resulting in discogenic pain. This model will be useful to test therapeutics and elucidate the basic mechanisms of IDD and discogenic pain.

Keyphrases

chronic pain
minimally invasive
ultrasound guided
pain management
neuropathic pain