Body mass index at diagnosis of a childhood brain tumor; a reflection of hypothalamic-pituitary dysfunction or lifestyle?
Ichelle M A A van RoesselJ van SchaikA Y N Schouten-van MeeterenA M BootH L Claahsen-van der GrintenS C ClementL van IerselK S HanA S P van TrotsenburgW P VandertopL C M KremerHanneke M van SantenPublished in: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer (2022)
Overweight or obesity at diagnosis of a childhood brain tumor seems not to be associated with pituitary deficiencies. These results suggest that genetics and lifestyle may be more important etiologic factors for higher BMI at diagnosis in these children than hypothalamic dysfunction. To improve the long-term outcome of CBTS with regards to overweight and obesity, more attention should be given to lifestyle already at the time of brain tumor treatment.