Cerebral glucose metabolism and cognition in newly diagnosed Parkinson's disease: ICICLE-PD study.
Michael J FirbankA J YarnallR A LawsonG W DuncanT K KhooG S PetridesJ T O'BrienR A BarkerR J MaxwellD J BrooksD J BurnPublished in: Journal of neurology, neurosurgery, and psychiatry (2016)
Reductions in cortical FDG metabolism were present in newly diagnosed PD, and correlated with performance on neuropsychological tests. A reduced baseline parietal metabolism is associated with risk of cognitive decline and may represent a potential biomarker for this state and the development of PD dementia.