Diagnostic value of 18 F-FDG PET-CT in detecting malignant peripheral nerve sheath tumors among adult and pediatric neurofibromatosis type 1 patients.

Ritchie T J GeitenbeekEnrico MartinLaura H GravenMartijn P G BroenMonique H M E AntenJochem A J van der PolCornelis VerhoefWalter Taal

Published in: Journal of neuro-oncology (2022)

F-FDG PET-CT offers adequate accuracy to detect MPNSTs. SUV values in pediatric MPNSTs may be lower, but tumor-to-liver ratios are not. By combining TLmean and SUVmax values, a 100% sensitivity can be achieved with acceptable specificity.

Keyphrases

peripheral nerve
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
peritoneal dialysis
prognostic factors
patient reported
structural basis