ACEA Attenuates Oxidative Stress by Promoting Mitophagy via CB1R/Nrf1/PINK1 Pathway after Subarachnoid Hemorrhage in Rats.

Binbing LiuYang TianYuchen LiPei WuYongzhi ZhangJiaolin ZhengHuaizhang Shi

Published in: Oxidative medicine and cellular longevity (2022)

This study demonstrated that ACEA alleviated oxidative stress and neurological dysfunction by promoting mitophagy after SAH, at least in part via the CB1R/Nrf1/PINK1 signaling pathway.

Keyphrases

oxidative stress
subarachnoid hemorrhage
brain injury
cerebral ischemia
induced apoptosis
signaling pathway
diabetic rats
ischemia reperfusion injury
dna damage
nlrp inflammasome
pi k akt
epithelial mesenchymal transition
cell proliferation