Differences in Post-mRNA Vaccination SARS-CoV-2 IgG Concentrations and Surrogate Virus Neutralization Test Response by HIV Status and Type of Vaccine: a Matched Case-Control Observational Study.
Matthew A SpinelliMichael J PelusoKara L LynchCassandra YunDavid V GliddenTimothy J HenrichSteven G DeeksMonica GandhiPublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2021)
Following SARS-CoV-2 mRNA vaccination, people living with HIV (PLWH) had lower surrogate virus neutralization test response (p=0.03) and a trend towards lower IgG response (p=0.08), particularly among those with lower CD4+T-cell counts and who received the BNT162b2 vaccine. Study of the impact of supplemental vaccine doses among PLWH is needed.