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Genome wide association analysis on semen volume and milk yield using different strategies of imputation to whole genome sequence in French dairy goats.

Estelle TalouarnPhilippe BardouIsabelle PalhièreClaire OgetVirginie Clémentnull nullGwenola Tosser-KloppRachel RuppChristèle Robert-Granié
Published in: BMC genetics (2020)
Even with very small reference populations, an acceptable imputation quality can be achieved in French dairy goats. GWAS on imputed sequences confirmed the existence of QTLs and identified new regions of interest in dairy goats. Adding identified candidates to a genotyping array and sequencing more individuals might corroborate the involvement of identified regions while removing potential imputation errors.
Keyphrases
  • genome wide association
  • high throughput
  • genetic diversity
  • single cell
  • genome wide
  • patient safety
  • risk assessment
  • human health
  • climate change
  • mass spectrometry