Association of Disease-Modifying Treatment With Outcome in Patients With Relapsing Multiple Sclerosis and Isolated MRI Activity.
Gabriel BstehMarie L AicherJanette F WaldeNik KrajncLukas HaiderGerhard TraxlerChristiane GradlSalmen AnkeKatharina RiedlPaulina PoskaitePhilipp LeyendeckerPatrick AltmannMichael AuerKlaus BerekFranziska Di PauliBarbara KornekFritz LeutmezerPaulus Stefan RommerGudrun ZulehnerTobias ZrzavyFlorian DeisenhammerAndrew ChanThomas BergerRobert HoepnerHelly HammerHarald HegenPublished in: Neurology (2024)
This study provides Class III evidence that clinically stable patients with MS on low-/moderate-efficacy DMT with ≥3 new T2L on MRI who escalate DMT have a reduced risk of relapse and Expanded Disability Status Scale progression.