Genetic risk scores and hallucinations in patients with Parkinson disease.

Cynthia D J KustersKimberly C PaulAline Duarte FolleAdrienne M KeenerJeff M BronsteinValerija DobricicOle-Bjørn TysnesLars BertramGuido AlvesJanet S SinsheimerChristina M LillJodi Maple-GrødemBeate R Ritz

Published in: Neurology. Genetics (2020)

These results suggest that mechanisms for hallucinations in PD may in part be driven by the same genetic architecture that leads to cognitive decline in AD, especially by APOE.

Keyphrases

cognitive decline
parkinson disease
mild cognitive impairment
deep brain stimulation
genome wide
copy number
metabolic syndrome
high fat diet
dna methylation
type diabetes
skeletal muscle