Multiplex fluorescence in situ hybridisation to detect anaplastic lymphoma kinase and ROS proto-oncogene 1 receptor tyrosine kinase rearrangements in lung cancer cytological samples.

Federica Zito MarinoGiulio RossiImmacolata CozzolinoMarco MontellaMariacarolina MicheliGiuseppe BoginaEnrico MunariMatteo BrunelliRenato Franco

Published in: Journal of clinical pathology (2019)

Multiplex ALK/ROS1 FISH probe test is a useful tool to detect simultaneously ALK-rearrangement and ROS1-rearrangement on a single slide in cytological specimens with a small amount of biomaterial.

Keyphrases

tyrosine kinase
epidermal growth factor receptor
cell death
dna damage
reactive oxygen species
advanced non small cell lung cancer
fine needle aspiration
high throughput
real time pcr
diffuse large b cell lymphoma
single molecule
quantum dots
living cells
energy transfer
fluorescent probe