Deciphering the role of platelets in severe allergy by an integrative omics approach.

Carmela Pablo-Torres Elena Izquierdo ÁlvarezTiak Ju TanDavid ObesoJanice A LayhadiJavier Sánchez-SolaresLeticia Mera-BerriatuaJosé Luis Bueno-CabreraMaría Del Mar Reaño-MartosAlfredo Iglesias-CadarsoCoral BarbasCristina Gomez-CasadoAlma Villaseñor Domingo Barber M H Mohamed Shamji María M Escribese

Published in: Allergy (2022)

This study demonstrates that platelet lipid, mRNA, and protein content is different according to allergy severity. These findings suggest that platelet load is a potential source of biomarkers and a new chance for therapeutic targets in severe inflammatory pathologies.

Keyphrases

early onset
binding protein
oxidative stress
human health
risk assessment
amino acid
climate change