Clinical Intricacies and Advances in Neuroendocrine Tumors: An Organ-Based Multidisciplinary Approach.
Luigi AsmundoValentina AmbrosiniMark A AndersonStefano FantiWilliam R BradleyDavide CampanaAmirkasra MojtahedRyan ChungShaunagh McdermottSubba DigumarthyStephan UrsprungKonstantin NikolauFlorian J FintelmannMichael BlakeCarlos Fernandez-Del CastilloMotaz QadanAnkur PandeyJeffrey W ClarkOnofrio A CatalanoPublished in: Journal of computer assisted tomography (2024)
Neuroendocrine neoplasms (NENs) are rare neoplasms originating from neuroendocrine cells, with increasing incidence due to enhanced detection methods. These tumors display considerable heterogeneity, necessitating diverse management strategies based on factors like organ of origin and tumor size. This article provides a comprehensive overview of therapeutic approaches for NENs, emphasizing the role of imaging in treatment decisions. It categorizes tumors based on their locations: gastric, duodenal, pancreatic, small bowel, colonic, rectal, appendiceal, gallbladder, prostate, lung, gynecological, and others. The piece also elucidates the challenges in managing metastatic disease and controversies surrounding MEN1-neuroendocrine tumor management. The article underscores the significance of individualized treatment plans, underscoring the need for a multidisciplinary approach to ensure optimal patient outcomes.
Keyphrases
- small bowel
- neuroendocrine tumors
- prostate cancer
- squamous cell carcinoma
- small cell lung cancer
- induced apoptosis
- mass spectrometry
- cell death
- rectal cancer
- cell cycle arrest
- cell proliferation
- signaling pathway
- smoking cessation
- endoplasmic reticulum stress
- health insurance
- quantum dots
- sensitive detection
- benign prostatic hyperplasia
- real time pcr
- ulcerative colitis