Fine needle aspiration biopsy of parathyroid; is it meaningful? A cytologic study of 81 cases with histological and clinical correlations.

Elwira Bakuła-ZalewskaJoanna DługosińskaAgata Stanek-WideraPiotr GóralskiJacek GałczyńskiAgnieszka ŻyłkaMonika DurzyńskaMarek Dedecjus

Published in: Cytopathology : official journal of the British Society for Clinical Cytology (2024)

High cellularity scattered naked nuclei, cribriform and three-dimensional patterns, stippled chromatin and oxyphilic cytoplasm are cytomorphologic features that favour parathyroid origin. A combination of these features with FNA-PTH assay and/or GATA3, PTH, and chromogranin-A immunostainings on cytologic specimens aid in the identification of parathyroid glands and the distinguishing of parathyroid from thyroid lesions.

Keyphrases

fine needle aspiration
ultrasound guided
transcription factor
gene expression
dna damage
high throughput
oxidative stress
bioinformatics analysis