Cancer-educated mammary adipose tissue-derived stromal/stem cells in obesity and breast cancer: spatial regulation and function.
Andreas RitterNina-Naomi KreisSusanne RothAlexandra FriemelBabek Kahn SafdarSamira Catharina HoockJulia Maria WildnerRoman AllertFrank LouwenChristine SolbachJuping YuanPublished in: Journal of experimental & clinical cancer research : CR (2023)
This study provides mechanistic insights into how obesity affects the phenotype of bASCs in the TME. Moreover, it highlights the molecular changes inside breast cancer cells upon cell-cell interaction with cancer-educated bASCs.