Premorbid functional reserve modulates the effect of rehabilitation in multiple sclerosis.
Letizia CastelliLaura De GiglioShalom HaggiagArianna TrainiFrancesca De LucaSerena RuggieriLuca ProsperiniPublished in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2020)
We hypothesize that premorbid physical and intellectual activities not only act as a buffer for limiting the MS-related damage but also as functional reserve that can be retrieved by task-oriented training to promote recovery through rehabilitation.