Pre-treatment amino acids and risk of paclitaxel-induced peripheral neuropathy in SWOG S0221.
Ciao-Sin ChenGary R ZirpoliG Thomas BuddWilliam E BarlowLajos PusztaiGabriel N HortobagyiKathy S AlbainAndrew K GodwinAlastair ThompsonNorah L HenryChristine B AmbrosoneKathleen A StringerDaniel Louis HertzPublished in: Cancer chemotherapy and pharmacology (2024)
This analysis showed that pre-treatment serum amino acid concentrations are not strongly predictive of CIPN severity. Prospectively designed studies that assess non-amino acid metabolomics predictors are encouraged.