Performance evaluation of an amplicon-based next-generation sequencing panel for BRCA1 and BRCA2 variant detection.

Kuenyoul ParkMin Kyu KimTaegeun LeeJinyoung HongHyun-Ki KimSunyoung AhnYoung-Jae LeeJisun KimShin-Wha LeeJong Won LeeWoochang LeeSail ChunByung Ho SonKyung Hae JungYong-Man KimWon-Ki MinSei-Hyun Ahn

Published in: Journal of clinical laboratory analysis (2020)

Our findings confirm that the analytic performance of the AmpliSeq panel is satisfactory, with high sensitivity and specificity.

Keyphrases

breast cancer risk
copy number
loop mediated isothermal amplification
label free
circulating tumor
gene expression
quantum dots