A systematic review and an individual patient data meta-analysis of ivermectin use in children weighing less than fifteen kilograms: Is it time to reconsider the current contraindication?
Podjanee JittamalaWuelton MonteiroMenno Roderick SmitBelen PedriqueSabine SpechtCarlos J ChaccourCéline DardPascal Del GiudiceVirak KhieuAnnabel MaruaniVirgilio Efrain Failoc-RojasMaria Del Mar Saéz de OcarizAntonio Soriano-ArandesJaime Piquero-CasalsAnne FaisantMarie-Pierre Brenier-PinchartDavid WimmersbergerJean T CoulibalyJennifer KeiserFranck BoraleviOliver SokanaMichael MarksDaniel EngelmanLucia RomaniAndrew C SteerLorenz von SeidleinNicholas J WhiteElinor HarrissKasia StepniewskaGeorgina S HumphreysKalynn KennonPhilippe J GuerinKevin C KobylinskiPublished in: PLoS neglected tropical diseases (2021)
Existing limited data suggest that oral ivermectin in children weighing less than 15 kilograms is safe. Data from well-designed clinical trials are needed to provide further assurance.