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Phages are unrecognized players in the ecology of the oral pathogen Porphyromonas gingivalis.

Cole B MatrishinElaine M HaaseFloyd E DewhirstJessica L Mark WelchFabiola Miranda-SanchezTsute ChenDonald C MacFarlandKathryn M Kauffman
Published in: Microbiome (2023)
This work definitively establishes that phages are a major unrecognized force shaping the ecology and intra-species strain-level diversity of the well-studied oral pathogen Pg. The foundational phage sequence datasets and model systems that we establish here add to the rich context of all that is already known about Pg, and point to numerous avenues of future inquiry that promise to shed new light on fundamental features of phage impacts on human health and disease broadly. Video Abstract.
Keyphrases
  • human health
  • risk assessment
  • pseudomonas aeruginosa
  • candida albicans
  • climate change
  • single molecule
  • big data
  • current status
  • machine learning
  • rna seq
  • amino acid
  • deep learning
  • solid state