Respiratory parameters on diagnostic sleep studies predict survival in patients with amyotrophic lateral sclerosis.
Markus EngelChristian GlatzCornelia HelmlePeter YoungBianca DrägerMatthias BoentertPublished in: Journal of neurology (2021)
In patients with ALS, EMBE > 2 mmol/l predicts nocturnal hypercapnia and shorter survival. Negative effects of sleep-disordered breathing on survival are statistically abolished by sustained NIV.