Quantitative evaluation of very early cartilage damage in experimental osteoarthritis using scanning electron microscopy.
Virgínia Cláudia Carneiro Girão-CarmonaMirna Marques BezerraFernanda Maria Aragão Ximenes PortoAna Carolina Matias Dinelly PintoRodolfo de Melo NunesAnelise Maria Costa Vasconcelos AlvesClaudio Cabral CampelloAna Caroline Rocha de Melo LeiteGerly Anne de Castro BritoFrancisco Airton Castro RochaPublished in: Advances in rheumatology (London, England) (2022)
This is the first demonstration of very early quantitative changes in the cartilage of mice subjected to posttraumatic experimental OA using SEM, revealing increased roughness and thickness as early as 3 days post surgery. These changes may be used as early surrogates for later joint damage in experimental OA.