Synthesis of DOTA-pyridine chelates for 64Cu coordination and radiolabeling of αMSH peptide.

Hua YangFeng GaoBrooke McNeilChengcheng ZhangZheliang YuanStefan ZeislerJoel KumlinJutta ZeislerFrançois BénardCaterina RamogidaPaul Schaffer

Published in: EJNMMI radiopharmacy and chemistry (2021)

DOTA-xPy (x = 1-3) are promising chelators for 64Cu. Further in vivo evaluation is necessary to assess the full potential of these chelators as a tool to enable further theranostic radiopharmaceutical development.

Keyphrases

pet ct
pet imaging
aqueous solution
photodynamic therapy
metal organic framework
positron emission tomography
fluorescence imaging
human health
risk assessment
computed tomography