Circulating Dendritic Cells from Celiac Disease Patients Display a Gut-Homing Profile and are Differentially Modulated by Different Gliadin-Derived Peptides.

Celia Escudero-HernándezÁlvaro MartínRodrigo de Pedro AndrésLuis Fernández-SalazarJosé Antonio GarroteDavid BernardoEduardo Arranz

Published in: Molecular nutrition & food research (2020)

Distinct gliadin-derived peptides elicit different effects on cDC2 phenotype and function. This effect is compatible with a model where diverse gliadin peptides may cooperate to promote full cDC2 activation and the subsequent T-cell response in genetically predisposed individuals.

Keyphrases

celiac disease
dendritic cells
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
amino acid
immune response
cell cycle
prognostic factors