Anti-VEGF therapy selects for clones resistant to glucose starvation in ovarian cancer xenografts.

Daniele BosoMartina TognonMatteo CurtarelloSonia MinuzzoIlaria PigaValentina BrilloElisabetta LazzariniJessica CarletLudovica MarraChiara TrentoAndrea RasolaIonica MasgrasLeonardo CaporaliFabio Del BenGiulia BrisottoMatteo TurettaRoberta PastorelliLaura BrunelliFilippo NavagliaGiovanni EspositoAngela GrassiStefano Indraccolo

Published in: Journal of experimental & clinical cancer research : CR (2023)

A glucose-deprivation resistant population of ovarian cancer cells showing druggable OXPHOS-dependent metabolic traits is enriched in experimental tumors treated by anti-VEGF therapy.

Keyphrases

vascular endothelial growth factor
endothelial cells
genome wide
gene expression
metabolic syndrome
type diabetes
dna methylation