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Dysregulated MAPK signaling pathway in acute myeloid leukemia with RUNX1 mutations.

Mingmin HeYongqin JiaYan WangXiongwei Cai
Published in: Expert review of hematology (2022)
RUNX1 could modulate MAPK pathway, which may provide a potential therapeutic target for AML patients with RUNX1 mutations.
Keyphrases
  • signaling pathway
  • pi k akt
  • transcription factor
  • induced apoptosis
  • epithelial mesenchymal transition
  • oxidative stress
  • acute myeloid leukemia
  • risk assessment
  • human health
  • climate change