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New molecular tools for meningitis diagnostics in Ethiopia - a necessary step towards improving antimicrobial prescription.

Guro K BårnesEsayas Kebede GudinaMelkamu BerhaneAlemseged AbdissaGetnet TesfawGemeda AbebeSiri Laura FeruglioDominique A CaugantHannah Joan Jørgensen
Published in: BMC infectious diseases (2018)
A rapid molecular diagnostic system was successfully implemented in an Ethiopian setting without previous experience of molecular diagnostics. Viral meningitis was diagnosed for the first time in routine clinical practice in Ethiopia, and viral agents were the most commonly detected microorganisms in CSF. This study illustrates the potential of rapid diagnostic tests for reducing antibiotic usage in suspected meningitis cases. However, the cost of consumables for the molecular diagnostic system used in this study limits its use in low-income countries.
Keyphrases
  • clinical practice
  • cerebrospinal fluid
  • single molecule
  • pulmonary embolism
  • climate change