Decidualization-derived cAMP promotes decidual NK cells to be angiogenic phenotype.

Xueling JinLie MaoWeijie ZhaoLu LiuYanhong LiDa-Jin Li Ying Zhang Mei-Rong Du

Published in: American journal of reproductive immunology (New York, N.Y. : 1989) (2022)

These findings suggest that dNK cells display an angiogenic phenotype that can be induced by decidualized cAMP signaling. Our study indicates the significance of decidualization-derived cAMP in regulating angiogenesis of decidual NKs and reveals complex crosstalk between different cell types in a critical period during early pregnancy.

Keyphrases

nk cells
binding protein
induced apoptosis
protein kinase
cell cycle arrest
cell therapy
vascular endothelial growth factor
cell death