The microRNA-1908 up-regulation in the peripheral blood cells impairs amyloid clearance by targeting ApoE.

Z WangW QinC B WeiY TangL N ZhaoH M JinY LiQ WangX Q LuanJin-Cai He Jian-Ping Jia

Published in: International journal of geriatric psychiatry (2018)

Our study provides new insight into the mechanism of ApoE dysregulation in AD patients, and microRNA-1908 might be a therapeutic target for AD treatment.

Keyphrases

peripheral blood
end stage renal disease
cognitive decline
newly diagnosed
ejection fraction
induced apoptosis
chronic kidney disease
high fat diet
cell cycle arrest
type diabetes
oxidative stress
patient reported outcomes
skeletal muscle
adipose tissue