Association of endothelial and glycocalyx injury biomarkers with fluid administration, development of acute kidney injury, and 90-day mortality: data from the FINNAKI observational study.
Nina InkinenVille PettiläPäivi LakkistoAnne KuitunenSakari JukarainenStepani BendelOuti InkinenTero Ala-KokkoSuvi T Vaaranull nullPublished in: Annals of intensive care (2019)
VAP-1 and IL-6 associated with fluid administration on the first ICU day. After adjusting for confounders, sTM was associated with development of AKI after 12 h from ICU admission. SDC-1, Ang-2 and sTM were independently associated with an increased risk for 90-day mortality.