Recent Advances in Synthetic Methods by Photocatalytic Single-Electron Transfer Chemistry of Pyridine N -Oxides.

By adoption of the enabling technology of modern photoredox catalysis and photochemistry, the generation of reactive and versatile pyridine N -oxy radicals can be facilely achieved from single-electron oxidation of pyridine N -oxides. This Synopsis highlights recent methodologies mediated by pyridine N -oxy radicals in developing (1) pyridine N -oxide-based hydrogen atom transfer catalysts for C(sp 3 )-H functionalizations and (2) β-oxyvinyl radical-mediated cascade reactions. In addition, recent research revealed that direct photoexcitation of pyridine N -oxides allowed for the generation of alkyl carbon radicals from alkylboronic acids.