Exhausted Tumor-infiltrating CD39+CD103+ CD8+ T Cells Unveil Potential for Increased Survival in Human Pancreatic Cancer.

Laia Gorchs Carlos Fernandez Moro Ebba Asplund Marlies Oosthoek Martin Solders Poya Ghorbani Ernesto Sparrelid Elena Rangelova Johannes Matthias Löhr Helen Kaipe

Published in: Cancer research communications (2024)

Patients with pancreatic cancer with a high proportion of CD39+CD103+ CD8+ T cells exhibiting a tumor-reactive phenotype have improved survival rates, suggesting their potential utility in selecting candidates for immunotherapy trials.

Keyphrases

endothelial cells
free survival
human health
induced pluripotent stem cells
risk assessment