Standard ultra-staging compared to one-step nucleic acid amplification for the detection of sentinel lymph node metastasis in endometrial cancer patients: a retrospective cohort comparison.
Francesco FanfaniGiorgia MonterossiMaria Letizia Di MeoEleonora La FeraFederica Dell'OrtoAlessandro GioèMaria LamannaDebora FerrariElena De PontiPatrizia PeregoStefano RestainoRonsini CarloGian Franco ZannoniFabio LandoniGiovanni ScambiaAlessandro BudaPublished in: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society (2020)
The OSNA assay detected a higher rate of micrometastasis and a lower rate of macrometastasis and ITC when compared with SU. The clinical and prognostic impact of ITC is debatable and controversial. Further studies are needed to clarify the respective roles of the OSNA and SU methods, and the possible role of ITC in the prognosis of patients with apparent early-stage endometrial cancer.
Keyphrases
- endometrial cancer
- nucleic acid
- sentinel lymph node
- early stage
- lymph node
- end stage renal disease
- newly diagnosed
- neoadjuvant chemotherapy
- chronic kidney disease
- peritoneal dialysis
- high throughput
- high resolution
- label free
- squamous cell carcinoma
- magnetic resonance imaging
- radiation therapy
- mass spectrometry
- case control
- patient reported
- locally advanced
- quantum dots