Imaging Biomarkers of Alzheimer Disease in Multiple Sclerosis.

Burcu ZeydanVal J LoweRoss R ReichardScott A PrzybelskiTimothy G LesnickChristopher G SchwarzMatthew L SenjemJeffrey L GunterJoseph E ParisiMary M MachuldaPrashanthi VemuriMichelle M MielkeDavid S KnopmanRonald C PetersenClifford R JackOrhun H KantarciKejal Kantarci

Published in: Annals of neurology (2020)

Although both β-amyloid and tau are biomarkers of cognitive aging and AD, cortical β-amyloid deposition was lower in MS than age-matched controls, suggesting that some aspect of MS pathobiology retards the accumulation of β-amyloid but not the accumulation of tau. ANN NEUROL 2020;87:556-567.

Keyphrases

multiple sclerosis
mass spectrometry
ms ms
cerebrospinal fluid
high resolution
white matter
neural network