A predictive finite element model was developed to investigate the best configuration of a fixation pins system consisting of two K-wires inserted in a synthetic model (Sawbones ® ) at different angles and secured to a connecting rod. Two key parameters were considered to determine the best configuration delivering the higher pull-out strength and lower pull-out length: the diameter and insertion angle. Results show that as the diameter and insertion angle increased, the pull-out force increased, while the pull-out length decreased. Results are successfully compared with available experimental data in literature. This model can be used as an alternative to experimental study.