Weight-loss Independent Clinical and Metabolic Biomarkers Associated with Type 2 Diabetes Remission Post-bariatric/metabolic Surgery.
Kusuma ChaiyasootNaomi S SakaiRoxanna ZakeriJanine MakaronidisLuís CrisóstomoMarco G AlvesWei GanChloe FirmanFriedrich C JassilMargaret A Hall-CraggsStuart A TaylorRachel L BatterhamPublished in: Obesity surgery (2023)
We highlight a potentially novel relationship between VAT and BCAAs, which may play a role in glucoregulatory control. Improvement in β-cell function, and the role ghrelin plays in its recovery, is likely another key factor influencing T2D remission post-surgery. These findings suggest that adjunctive approaches that target VAT loss and restoration of BCAA metabolism might achieve higher rates of long-term T2D remission post-surgery.