Differences in epitope-specific antibodies to pertussis toxin after infection and acellular vaccinations.

Aapo Knuutila Tine DalbyAlex-Mikael BarkoffCharlotte Sværke JørgensenKurt FuurstedJussi MertsolaKevin MarkeyQiushui He

Published in: Clinical & translational immunology (2020)

The high amount of 7E10-specific antibodies in patients suggests this epitope might be functionally relevant in protection. The overall characteristics of epitope-specific antibodies are influenced by infection or vaccination background, by the used detoxification method of PT and by the amount of the toxin used in immunisation.

Keyphrases

escherichia coli
end stage renal disease
ejection fraction
monoclonal antibody
newly diagnosed
prognostic factors
peritoneal dialysis
patient reported