Rehmapicrogenin attenuates lipopolysaccharide-induced podocyte injury and kidney dysfunctions by regulating nuclear factor E2-related factor 2/antioxidant response element signalling.
Xiaohong MaGuandong LiYufeng ShiZhitao ShangPublished in: Nephrology (Carlton, Vic.) (2024)
Rehmapicrogenin relieves the podocyte injury and renal dysfunctions through activating the Nrf2/ARE pathway to inhibit apoptosis and oxidative stress.
Keyphrases
- oxidative stress
- lipopolysaccharide induced
- nuclear factor
- inflammatory response
- toll like receptor
- diabetic rats
- diabetic nephropathy
- dna damage
- ischemia reperfusion injury
- induced apoptosis
- high glucose
- signaling pathway
- endoplasmic reticulum stress
- immune response
- cell cycle arrest
- cell death
- endothelial cells
- heat shock
- cell proliferation