Electrochemical Gene Amplification Signal Detection of Disposable Biochips Using Electrodes.
Gyo-Rim KimJi-Soo HwangJong-Dae KimYu-Seop KimChan-Young ParkPublished in: Sensors (Basel, Switzerland) (2022)
Real-time Polymerase Chain Reaction (RT-PCR), a molecular diagnostic technology, is spotlighted as one of the quickest and fastest diagnostic methods for the actual coronavirus (SARS-CoV-2). However, the fluorescent label-based technology of the RT-PCR technique requires expensive equipment and a sample pretreatment process for analysis. Therefore, this paper proposes a biochip based on Electrochemical Impedance Spectroscopy (EIS). In this paper, it was possible to see the change according to the concentration by measuring the impedance with a chip made of two electrodes with different shapes of sample DNA.
Keyphrases
- label free
- sars cov
- single molecule
- real time pcr
- solid state
- gold nanoparticles
- reduced graphene oxide
- respiratory syndrome coronavirus
- circulating tumor
- ionic liquid
- nucleic acid
- molecularly imprinted
- high resolution
- living cells
- genome wide
- cell free
- circulating tumor cells
- high throughput
- genome wide identification
- computed tomography
- electron transfer