Hospitalized Patients With COVID-19 Have Higher Plasma Aldosterone-Renin Ratio and Lower ACE Activity Than Controls.
Nisha I ParikhFolagbayi ArowoloMatthew S DurstenfeldGregory NahJoyce NjorogeEric VittinghoffCarlin S LongPeter GanzDavid PearcePriscilla HsueAlan H S WuNegin HajizadehKathleen D LiuKara L LynchPublished in: Journal of the Endocrine Society (2022)
High ARR, independent of BMI, may be a risk marker for COVID-19 hospitalization. Serum ACE activity was lower in patients with COVID-19 vs controls at the beginning of their hospitalization and then increased to similar levels as controls, possibly due to lung injury, which improved with inpatient disease management.