Brain changes and fast cognitive and motor decline in older adults.

Giulia GrandeDavide Liborio VetranoGrégoria KalpouzosAnna-Karin Welmer Erika J Laukka Anna MarsegliaLaura FratiglioniDebora Rizzuto

Published in: The journals of gerontology. Series A, Biological sciences and medical sciences (2022)

Concurrent cognitive and motor decline is accompanied by rapidly evolving and complex brain pathology involving both gray and white matter. Isolated cognitive and motor declines seem to exhibit brain damage with different qualitative features.

Keyphrases

white matter
resting state
multiple sclerosis
functional connectivity
cerebral ischemia
physical activity
systematic review
oxidative stress
squamous cell carcinoma