Measurement of 8-hydroxy-2'-deoxyguanosine in serum and cerebrospinal fluid of horses with neuroaxonal degeneration and other causes of proprioceptive ataxia.

Megan PalmisanoJeaneen KulpSusan BenderDarko StefanovskiMary RobinsonAmy Johnson

Published in: Journal of veterinary internal medicine (2024)

Eight-OHdG did not aid in antemortem diagnosis of NAD/DM in this cohort of horses. At the time of diagnosis horses with NAD/DM do not have ongoing oxidative stress.

Keyphrases

cerebrospinal fluid
oxidative stress
dna damage
early onset
glycemic control
type diabetes
metabolic syndrome
heat shock