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Protective role of 17β-estradiol in alcohol-associated liver fibrosis is mediated by suppression of integrin signaling.

Kruti NatarajMichael SchonfeldAdriana RodriguezIrina Tikhanovich
Published in: Hepatology communications (2024)
Taken together, estrogen signaling protects mice from liver disease induced by a combination of alcohol and high-fat diet through upregulation of Prmt6 and suppression of integrin signaling.
Keyphrases
  • high fat diet
  • liver fibrosis
  • adipose tissue
  • insulin resistance
  • estrogen receptor
  • type diabetes
  • signaling pathway
  • long non coding rna